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Clinical Pharmacology
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In the INDEX study, a one-year, double-blind, placebo-controlled trial of obese patients, dexfenfluramine, in conjunction with a reduced-calorie diet, produced a significant reduction in weight during the first 4 to 6 months. This response was maintained during continuation of therapy (up to 12 months of treatment). The percentage of patients who achieved various levels of weight loss at 1 year are shown below.
Generic Name: Dexfenfluramine (FDA Removed From US Market 9/15/97)
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