There is no specific treatment for overdose with fenofibrate. General supportive care of the patient is indicated, including monitoring of vital signs and observation of clinical status, should an overdose occur. If indicated, elimination of unabsorbed drug should be achieved by emesis or gastric lavage; usual precautions should be observed to maintain the airway. Because fenofibrate is highly bound to plasma proteins, hemodialysis should not be considered.

• Fenofibrate is contraindicated in patients with severe renal dysfunction, including those receiving dialysis [see Clinical Pharmacology]
• Fenofibrate is contraindicated in patients with active liver disease, including those with primary biliary cirrhosis and unexplained persistent liver function abnormalities [see Warnings and Precautions]
• Fenofibrate is contraindicated in patients with gallbladder disease [see Warnings and Precautions]
• Fenofibrate is contraindicated in nursing mothers [see Use in Specific Populations]
• Fenofibrate is contraindicated in patients who have a known hypersensitivity to fenofibrate, such as severe skin rashes, including Stevens-Johnson syndrome and toxic epidermal necrolysis. [see Warnings and Precautions]

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