Immune Response in Geriatric Patients: An open-label, randomized, multicenter study conducted in Europe compared the immunogenicity of FLUARIX with 2 European-licensed influenza vaccines in subjects >60 years of age (mean age 68). Additionally, 2 open-label studies evaluated immune responses to FLUARIX among adults ≥ 18 years of age. Post-hoc analyses combined results from these 3 studies in the subgroup of subjects ≥ 65 years of age (n = 246) who received FLUARIX. In these analyses, the lower limits of the 2-sided 95% confidence intervals of the percentages of subjects achieving an HI titer ≥ 1:40 were greater than 70% and for subjects achieving seroconversion were greater than 40%, for each antigen.

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