Gabitril
GABITRILÒ
(tiagabine hydrochloride) Tablets
Rx only
DRUG DESCRIPTION
GABITRIL (tiagabine HCl) is an antiepilepsy drug available as 2 mg, 4 mg, 6 mg, 8, mg, 10 mg, 12 mg, and 16 mg tablets for oral administration. Its chemical name is (-)-(R)-1-[4,4-Bis(3-methyl-2-thienyl)-3-butenyl]nipecotic acid hydrochloride, its molecular formula is C20H25NO2S2 HCl, and its molecular weight is 412.0. Tiagabine HCl is a white to off-white, odorless, crystalline powder. It is insoluble in heptane, sparingly soluble in water, and soluble in aqueous base. The structural formula is:

Inactive Ingredients
GABITRIL tablets contain the following inactive ingredients: Ascorbic acid, colloidal silicon dioxide, crospovidone, hydrogenated vegetable oil wax, hydroxypropyl cellulose, hypromellose, lactose, magnesium stearate, microcrystalline cellulose, pregelatinized starch, stearic acid, and titanium dioxide. In addition, individual tablets contain:
| 2 mg tablets: FD&C Yellow No. 6. |
| 4 mg tablets: D&C Yellow No. 10. |
| 6 mg tablets: FD&C Blue No. 2. |
| 8 mg tablets: Dye Free. |
| 10 mg tablets: D&C Red No. 30. |
| 12 mg tablets: D&C Yellow No. 10 and FD&C Blue No. 1. |
| 16 mg tablets: FD&C Blue No. 2. |
Generic Name: Tiagabine Hydrochloride
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