Guaifenesin is an expectorant. Expectorants promote and facilitate the removal of respiratory tract secretions by increasing sputum volume and making sputum less viscous. Guaifenesin is readily absorbed from the gastrointestinal tract and is rapidly metabolized and excreted in the urine. Guaifenesin has a plasma half-life of one hour. The major urinary metabolite is beta-(2-methoxyphenoxy) lactic acid.

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