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PRECAUTIONS
TO PRESERVE THE LONG-ACTING EFFECT, DO NOT CRUSH OR CHEW TABLETS BEFORE INGESTION.
Carcinogenesis, Mutagenesis, Impairment of Fertility
No data are available on the long term potential of guaifenesin for carcinogenesis, mutagenesis or impairment of fertility in animals or humans.
Teratogenic Effects: Pregnancy Category C. Animal reproduction studies have not been conducted with guaifenesin. Safe use in pregnancy has not been established relative to possible adverse effects on fetal development. Therefore, this product should not be used in pregnant patients, unless in the judgement of the physician, the potential benefits outweigh possible hazards.
Nursing Mothers
It is not known whether guaifenesin is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when these products are administered to a nursing mother and a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Pediatric Use
Safety and effectiveness in pediatric patients under 6 years has not been established.
Laboratory Test Interactions
G uaifenesin interferes with the calorimetric determination of 5-HIAA (5-hydroxyindoleacetic acid) and VMA (vanillylmandelic acid).
Generic Name: Guaifenesin
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