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Eldopaque

Clinical Pharmacology
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CLINICAL PHARMACOLOGY

Eldopaque

Topical application of hydroquinone produces a reversible depigmentation of the skin by inhibition of the enzymatic oxidation of tyrosine to 3,4-dihydroxyphenylalanine (dopa) (Denton, C. et al, 1952) 1 and suppression of other melanocyte metabolic processes (Jimbow, K. et al, 1974) 2.

Exposure to sunlight or ultraviolet light will cause repigmentation which may be prevented by the broad spectrum sunscreen agents contained in Solaquin Forte (Parrish, J. A. et al, 1978) 3.



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