Crixivan
OVERDOSE
There have been more than 60 reports of acute or chronic human overdosage (up to 23 times the recommended total daily dose of 2400 mg) with CRIXIVAN. The most commonly reported symptoms were renal (e.g., nephrolithiasis/urolithiasis, flank pain, hematuria) and gastrointestinal (e.g., nausea, vomiting, diarrhea).
It is not known whether CRIXIVAN is dialyzable by peritoneal or hemodialysis.
CONTRAINDICATIONS
CRIXIVAN is contraindicated in patients with clinically significant hypersensitivity to any of its components.
Inhibition of CYP3A4 by CRIXIVAN can result in elevated plasma concentrations of the following drugs, potentially causing serious or life-threatening reactions:
Table 7 Drug Interactions With Crixivan: Contraindicated Drugs
| Drug Class | Drugs Within Class That Are Contraindicated With CRIXIVAN |
| Antiarrhythmics | amiodarone |
| Ergot derivatives | dihydroergotamine, ergonovine, ergotamine, methylergonovine |
| Sedative/hypnotics | midazolam, triazolam, alprazolam |
| GI motility agents | cisapride |
| Neuroleptics | pimozide |
Generic Name: Indinavir Sulfate
HIV Test for Early Detection
There is a test that may help detect the virus sooner, so patients can start treatment much faster. See more WebMD Videos »
WebMD Daily
Get breaking medical news.
Crixivan
Related Drugs
Health Resources
2008 Election & Health Care on WebMD. Get Informed.
Updated & New
RxList does not provide medical advice, diagnosis or treatment.