Konyne
DRUG DESCRIPTION
Factor IX Complex, Konyne® 80, heat-treated at 80°C for 72 hours, is a sterile, dried, plasma fraction comprising coagulation factors II, IX, X and low levels of factor VII.
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Factor: Synonyms: II prothrombin VII proconvertin IX plasma thromboplastin component, PTC, Christmas factor X Stuart-Prower factor |
Konyne 80 is standardized in terms of factor IX content and each vial of Konyne 80 is labeled for factor IX. One international unit (IU) of factor IX as defined by the World Health Organization standard for blood coagulation factor IX is approximately equal to the level of factor IX found in 1.0 mL of fresh, normal plasma.
The factor IX content is approximately 50 times purified over whole plasma, and when reconstituted as directed, Konyne 80 contains 25 times as much factor IX as an equal volume of fresh plasma. Konyne 80, containing approximately 1000 IU of factor IX administered in 40 mL, contains the factor IX content of 1 liter of fresh plasma. Konyne 80 must be administered intravenously.
Generic Name: Factor IX Complex
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Konyne
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