Lodosyn (Carbidopa) drug description - FDA approved labeling for prescription drugs and medications at RxList

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Lodosyn

Drug Description

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TABLETS

LODOSYN^®

(CARBIDOPA)

When LODOSYN* (Carbidopa) is to be given to carbidopa-naive patients who are being treated with levodopa, the two drugs should be given at the same time, starting with no more than 20 to 25 percent of the previous daily dosage of levodopa when given without LODOSYN (Carbidopa). At least twelve hours should elapse between the last dose of levodopa and initiation of therapy with LODOSYN (Carbidopa) and levodopa. See the WARNINGS and DOSAGE AND ADMINISTRATION sections before initiating therapy.

DRUG DESCRIPTION

Carbidopa, an inhibitor of aromatic amino acid decarboxylation, is a white, crystalline compound, slightly soluble in water, with a molecular weight of 244.3. It is designated chemically as (¾)-L-a-hydrazino-a-methyl-Β-(3,4-dihydroxybenzene) propanoic acid monohydrate. Its empirical formula is C₁₀H₁₄N₂O₄·H₂₀, and its structural formula is: