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Lorabid

Clinical Pharmacology
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Clinical Pharmacology


Study 2: In a second controlled clinical study of cystitis, performed in Europe, loracarbef was compared to an oral quinolone. In this study, using very strict evaluability criteria and microbiologic and clinical response criteria at the 5- to 9-day post therapy follow-up, the following bacterial eradication rates were obtained (see TABLE 11).

TABLE 11 European Uncomplicated Cystitis Study: Loracarbef vs Quinolone
Efficacy
Pathogen % of Cases With Pathogens (n=189) Outcome
 E. coli 82.0%  Loracarbef eradication rate 7% less than quinolone (loracarbef eradication rate 81%)
 Other major
 Enterobacteriaceae
10.1%  Loracarbef eradication rate 32% less than quinolone (loracarbef eradication rate 50%)


Brand Name: Lorabid
Generic Name: Loracarbef
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