In addition to vaccination with LYMErix, people can further decrease their risk of acquiring tick-borne infections by taking standard preventive measures (e.g., wearing longsleeved shirts, long pants rather than shorts, tucking pants into socks, treating clothing with tick repellent, and checking for and removing attached ticks).²

Patients, parents or guardians should be informed of the benefits and risks of immunization with LYMErix, and of the importance of completing the immunization series. As with any vaccine, it is important when a subject returns for the next dose in a series that he/she be questioned concerning the occurrence of any symptoms and/or signs after a previous dose of the same vaccine and adverse events be reported. The U. S. Department of Health and Human Services has established a Vaccine Adverse Events Reporting System (VAERS) to accept all reports of suspected adverse events after the administration of any vaccine. The VAERS toll-free number is 1-800-822-7967.

The duration of immunity following a complete schedule of immunization with LYMErix has not been established.

It is important to note that subjects with a prior history of B. burgdorferi infection may not have protection against subsequent disease²³ or asymptomatic infection.

Individuals should be informed that vaccination with LYMErix may induce a false-positive ELISA result for B. burgdorferi infection (see PRECAUTIONS, Laboratory Test Interactions). Patients should be advised to inform health care professionals that they have been immunized with LYMErix, since it may affect laboratory testing for diagnosing Lyme disease.

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