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HMS

Clinical Pharmacology
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CLINICAL PHARMACOLOGY

HMS® (medrysone) is a synthetic corticosteroid with topical anti-inflammatory and anti-allergic activity. Corticosteroids inhibit the inflammatory response to inciting agents of mechanical, chemical, or immunological nature of edema, fibrin deposition, capillary dilation and leukocyte migration, capillary proliferation, deposition of collagen and scar formation. HMS® (medrysone) has less anti-inflammatory potency than 0.1% dexamethasone. Data from 2 uncontrolled studies 1-2 indicate that in patients with increased intraocular pressure and in those susceptible to a rise in intraocular pressure, there is less effect on pressure with HMS® than with dexamethasone or betamethasone.



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