Aside from possible ovarian hyperstimulation (see WARNINGS), little is known concerning the consequences of acute overdosage with menotropins.

Repronex is contraindicated in women who have:

1. A high FSH level indicating primary ovarian failure.

2. Uncontrolled thyroid and adrenal dysfunction.

3. An organic intracranial lesion such as a pituitary tumor.

4. The presence of any cause of infertility other than anovulation unless they are candidates for in vitro- fertilization.

5. Abnormal bleeding of undetermined origin.

6. Ovarian cysts or enlargement not due to polycystic ovary syndrome.

7. Prior hypersensitivity to menotropins.

8. Repronex is not indicated in women who are pregnant. There are limited human data on the effects of menotropins when administered during pregnancy.

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