Find a Drug
Advanced Search

Professional

Lopressor

Drug Description
font size

Lopressor®
(metoprolol tartrate) Tablets, USP
(metoprolol tartrate) Injection, USP

DRUG DESCRIPTION

Lopressor (metoprolol) is a Beta Blocker

Medical Author: Melissa Stöppler, MD
Medical Editor: Jay W. Marks, MD

The class of drugs called beta blockers were given their name because this class of medications counteracts the stimulatory effects of epinephrine (adrenaline) on the so–called beta–adrenergic receptors found in many body tissues, including the nervous system and heart. Normal stimulation of the beta receptors leads to a faster heartbeat along with the constriction of blood vessels, resulting in an overall increase in blood pressure.

Beta blockers, therefore, counteract stimuli that lead to an elevated blood pressure, resulting in a slower pulse rate and a reduction in blood pressure. Both these effects reduce the workload of the heart, so beta blockers are of value in treating the symptoms of angina pectoris, the chest pain brought on by narrowing of the coronary arteries that causes inadequate delivery of oxygen–rich blood to the heart muscle. Beta blockers also are prescribed as treatments for high blood pressure and have been shown to improve survival when administered following a heart attack.

Read more on Lopressor (metoprolol tartrate) and other Beta Blockers »

Lopressor, metoprolol tartrate USP, is a selective beta1-adrenoreceptor blocking agent, available as 50- and 100-mg tablets for oral administration and in 5-mL ampuls for intravenous administration. Each ampul contains a sterile solution of metoprolol tartrate USP, 5 mg, and sodium chloride USP, 45 mg, and water for injection USP. Metoprolol tartrate USP is (±)-1-(Isopropylamino)-3-[ p-(2-methoxyethyl)phenoxy]-2-propanol L-(+)- tartrate (2:1) salt, and its structural formula is

Lopressor (metoprolol tartrate) structural formula illustration

Metoprolol tartrate USP is a white, practically odorless, crystalline powder with a molecular weight of 684.82. It is very soluble in water; freely soluble in methylene chloride, in chloroform, and in alcohol; slightly soluble in acetone; and insoluble in ether.

Inactive Ingredients. Tablets contain cellulose compounds, colloidal silicon dioxide, D&C Red No. 30 aluminum lake (50-mg tablets), FD&C Blue No. 2 aluminum lake (100-mg tablets), lactose, magnesium stearate, polyethylene glycol, propylene glycol, povidone, sodium starch glycolate, talc, and titanium dioxide.

Brand Name: Lopressor
Generic Name: Metoprolol Tartrate
Bookmark this page:


WebMD Symptom Checker - Start Here Diseases & Conditions: A comprehensive A-Z listing

Soy for High Blood PressureSoy for High Blood Pressure
About 65 million Americans have high blood pressure and more and more are turning to alternative therapies. Here, we look at soy. See more WebMD Videos »

Hypertension

Get tips on handling your hypertension.