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Clinical Pharmacology
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CLINICAL PHARMACOLOGY

The major effects of morphine are on the central nervous system and the bowel. Opioids act as agonists, interacting with stereospecific and saturable binding sites or receptors in the brain and other tissues.

Morphine is about two-thirds absorbed from the gastrointestinal tract with the maximum analgesic ef-fect occurring 60 minutes post administration.



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