Patients receiving OMNISCAN should be instructed to inform their physician if they:

• are pregnant or breast feeding, or
• have a history of renal disease, convulsions, asthma or allergic respiratory disorders, or recent administration of gadolinium-based contrast.

Gadolinium-based contrast agents increase the risk for NSF among patients with acute or chronic severe renal insufficiency or acute renal insufficiency due to the hepato-renal syndrome. This risk may increase with repetitive or higher than recommended doses of a gadolinium-based contrast agent. Instruct patients at increased risk for NSF to contact their physician if they develop burning, itching, swelling, scaling, hardening and tightening of the skin; red or dark patches on the skin; stiffness in joints with trouble moving, bending or straightening the arms, hands, legs or feet; pain deep in the hip bones or ribs; or muscle weakness.

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