Penicillin VK
DRUG DESCRIPTION
Penicillin V potassium is the potassium salt of penicillin V. This chemically improved form combines acid stability with immediate solubility and rapid absorption. It is designated 4-thia-1-azabicyclo[3.2.0]-heptane-2-carboxylic acid, 3,3 -dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-, monopotassium salt, [2S-(2a,5a,6b)]-. The empirical formula is C16H17KN2O5S, and the molecular weight is 388.48.
Each tablet contains penicillin V potassium equivalent to 250 mg (400,000 units) or 500 mg (800,000 units) penicillin V. The tablets also contain lactose, magnesium stearate, povidone, starch, stearic acid, and other inactive ingredients.
After being mixed as directed, each 5 ml of the oral solution will contain penicillin V potassium equivalent to 250 mg (400,000 units) penicillin V. The suspension also contains citric acid, F D & C Red No. 40, flavors, saccharin, sodium citrate, and sucrose.
The potassium content of the tablets and oral solution is listed below (TABLE 1).
| TABLE 1 | ||
| Size | Potassium (mEq) | Potassium (mg) |
|---|---|---|
| TABLETS | ||
| 250 mg (400,000 units) | 0.72 | 28.06 |
| 500 mg (800,000 units) | 1.44 | 56.12 |
| ORAL SOLUTION | ||
| 250 mg (400,000 units) 5 ml | 0.72 | 28.06 |
Generic Name: Penicillin V Potassium
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Penicillin VK
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