PREPIDIL Gel contains dinoprostone as the naturally occurring form of prostaglandin E₂ (PGE₂) and is designated chemically as (5Z, 11a, 13E, 15S) - 11,15 -Dihydroxy-9-oxo-prosta-5, 13-dien-1-oic acid. The molecular formula is C₂₀H₃₂O₅ and the molecular weight is 352.5. Dinoprostone occurs as a white to off-white crystalline powder with a melting point within the range of 65º to 69ºC. It is soluble in ethanol, in 25% ethanol in water, and in water to the extent of 130mg/100mL. The active constituent of PREPIDIL Gel is dinoprostone 0.5mg/3g (2.5mL gel); other constituents are colloidal silicon dioxide NF (240mg/3g) and triacetin USP (2760mg/3g). Its chemical structure is:

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