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Serostim LQ

Overdosage & Contraindications
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OVERDOSE

Glucose intolerance can occur with overdosage. Long-term overdosage with growth hormone could result in signs and symptoms of acromegaly.

CONTRAINDICATIONS

Growth hormone therapy should not be initiated in patients with acute critical illness due to complications following open heart or abdominal surgery, multiple accidental trauma or acute respiratory failure. Two placebo-controlled clinical trials in non-growth hormone deficient adult patients (n=522) with these conditions revealed a significant increase in mortality (41.9% vs. 19.3%) among somatropin-treated patients (doses 5.3-8 mg/day) compared to those receiving placebo (see WARNINGS).

Serostim is contraindicated in patients with active neoplasia (either newly diagnosed or recurrent). Any anti-tumor therapy should be completed prior to starting therapy with Serostim. SerostimÃ? LQ should not be used in any patient with a known hypersensitivity to somatropin or any of the excipients.

Brand Name: Serostim LQ
Generic Name: Somatropin (rDNA origin) Inj

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