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Temovate Gel

Drug Description
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TEMOVATE®
(clobetasol propionate) Gel, 0.05%

FOR TOPICAL DERMATOLOGIC USE ONLY
NOT FOR OPHTHALMIC, ORAL, OR INTRA VAGINAL USE

DRUG DESCRIPTION

TEMOVATE (clobetasol propionate gel) Gel contains the active compound clobetasol propionate, a synthetic corticosteroid, for topical dermatologic use. Clobetasol, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineratocorticoid activity.

Chemically, clobetasol propionate is (118,168)- 21 -chforo-9-fluoro-11 -hydroxy-16-methyl-17- (1 -oxopropoxy)-pregna-1,4-diene-3,20-dione, and it has the following structural formula:

TEMOVATE (clobetasol propionate) structural formula illustration

Clobetasol propionate has the empirical formula C25H32CIFO5 and a molecular weight of 467. It is a white to cream-colored crystalline powder insoluble in water.

TEMOVATE Gel contains clobetasol propionate 0.5 mg/g in a base of propylene glycol, carbomer 934P, sodium hydroxide, and purified water.

Brand Name: Temovate Gel
Generic Name: Clobetasol Propionate Gel
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