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Teslascan

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TESLASCAN®50 µmol/mL (mangafodipir trisodium) Injection

DRUG DESCRIPTION

TESLASCAN® (mangafodipir trisodium) Injection is an intravenous contrast agent for magnetic resonance imaging.

TESLASCAN Injection is formulated with mangafodipir trisodium, a solution of trisodium trihydrogen (OC-6-13)-[[N,N- 1,2-ethanediylbis[N-[ [3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]- 4-pyridinyl]methyl]glycinato]] (8-)] manganate (6-).

Mangafodipir trisodium (C22H27MnN4Na3O14P2) has a molecular weight of 757.33 (anhydrous) and the manganese content of the molecule is 7.25%.

TESLASCAN Injection is a sterile, clear yellow solution. Each milliliter of TESLASCAN Injection contains 37.9 mg (or 50 µmol/mL) mangafodipir trisodium; ascorbic acid, 2.0 mg; sodium chloride, 2.0 mg; fodipir, 0.25 mg; and Water for Injection. The pH is adjusted to 8.8 ±0.4 with hydrochloric acid and/or sodium hydroxide. The osmolality is 298 mOsmol/kg water. TESLASCAN Injection does not contain a preservative.

Pertinent physicochemical data are provided below:

PHYSICOCHEMICAL DATA

 

@ 37°C

Viscosity (cP)

0.8

Density (g/mL)

1.02

Specific Gravity

1.03

Osmolality (mOsmol/kg water)

298

Brand Name: Teslascan
Generic Name: Mangafodipir
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