Dyrenium
DYRENIUM® (WellSpring)
brand of triamterene Capsules
50 mg and 100 mg
potassium-sparing diuretic
Rx only
DRUG DESCRIPTION
| Abnormal elevation of serum potassium levels (greater than or equal to 5.5 mEq/liter) can occur with all potassium-sparing agents, including DYRENIUM® triamterene. Hyperkalemia is more likely to occur in patients with renal impairment, and diabetes (even without evidence of renal impairment), elderly or severely ill patients. Since uncorrected hyperkalemia may be fatal, serum potassium levels must be monitored at frequent intervals especially in patients receiving DYRENIUM® triamterene, when dosages are changed or with any illness that may influence renal function. |
Dyrenium (triamterene) is a potassium-conserving diuretic.
Triamterene is 2,4,7-triamino-6-phenylpteridine. Its molecular weight is 253.27.
Its structual formula is:
At 50°C, triamterene is slightly soluble in water. It is soluble in dilute ammonia, dilute aqueous sodium hydroxide and dimethylformamide. It is sparingly soluble in methanol.
Each capsule for oral use, with opaque red cap and body, contains triamterene, 50 or 100 mg, and is imprinted with the product name DYRENIUM, strength (50 or 100) and WPC 002 (for the 50 mg strength) and WPC 003 (for the 100 mg strength). Inactive ingredients consist of benzyl alcohol, cetylpyridinium chloride, D&C Red No. 33, FD&C Yellow No. 6, gelatin, lactose, magnesium stearate, povidone, sodium lauryl sulfate, titanium dioxide and trace amounts of other inactive ingredients.
Generic Name: Triamterene
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