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VESIcare

Overdosage & Contraindications
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OVERDOSE

Acute

Overdosage with VESIcare can potentially result in severe anticholinergic effects and should be treated accordingly. The highest VESIcare dose given to human volunteers was a single 100 mg dose.

Chronic

Intolerable anticholinergic side effects (fixed and dilated pupils, blurred vision, failure of heel-to-toe exam, tremors and dry skin) occurred on day 3 in normal volunteers taking 50 mg daily (5 times the maximum recommended therapeutic dose) and resolved within 7 days following discontinuation of drug.

Treatment of Overdosage

In the event of overdose with VESIcare, treat with gastric lavage and appropriate supportive measures. ECG monitoring is also recommended.

CONTRAINDICATIONS

VESIcare is contraindicated in patients with urinary retention, gastric retention, uncontrolled narrow-angle glaucoma, and in patients who have demonstrated hypersensitivity to the drug substance or other components of the product.

Brand Name: VESIcare
Generic Name: Solifenacin Succinate

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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