Buprenex
Buprenex®
(buprenorphine hydrochloride) Injectable
DRUG DESCRIPTION
Proprietary name: Buprenex
Established name: buprenorphine HCI
Route of administration: INTRAVENOUS (C38276), INTRAMUSCULAR (C28161)
Active ingredients (moiety): buprenorphine HCI (buprenorphine)
| # | Strength | Form | Inactive ingredients |
| 1 | 0.324 : 1 | INJECTION, SOLUTION ( C42945) | anhydrous dextrose, water for injection, hydrochloric acid |
Buprenex (buprenorphine hydrochloride) is a narcotic under the Controlled Substances Act due to its chemical derivation from thebaine. Chemically, it is 17-(cyclopropylmethyl)-α-(1,1-dimethylethyl)-4, 5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6, 14- ethenomorphinan-7-methanol, hydrochloride [5α, 7α(S)]. Buprenorphine hydrochloride is a white powder, weakly acidic and with limited solubility in water. Buprenex is a clear, sterile, injectable agonist-antagonist analgesic intended for intravenous or intramuscular administration. Each ml of Buprenex contains 0.324 mg buprenorphine hydrochloride (equivalent to 0.3 mg buprenorphine), 50 mg anhydrous dextrose, water for injection and HCI to adjust pH. Buprenorphine hydrochloride has the molecular formula, C29H41NO4HCI, and the following structure:
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Generic Name: Buprenorphine
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Buprenex
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