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Levo Dromoran

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DRUG DESCRIPTION

Levo-Dromoran (levorphanol tartrate) is a potent opioid analgesic with empirical formula C 17 H 23 NO·C 4 H 6 O 6 ·2H 2 O and molecular weight 443.5. Each mg of levorphanol tartrate is equivalent to 0.58 mg levorphanol base. Chemically levorphanol is levo-3-hydroxy-N-methylmorphinan. The USP nomenclature is 17-methylmorphinan 3-ol tartrate (1:1)(Salt) dihydrate. The material has 3 asymmetric carbon atoms.

Levorphanol tartrate is a white crystalline powder, soluble in water and ether but insoluble in chloroform.

Each 1-mL ampul contains 2 mg levorphanol tartrate, 1.8 mg methyl paraben preservative, 0.2 mg propyl paraben preservative, sodium hydroxide to adjust pH to approximately 4.3 and Water for Injection.

Each milliliter in the 10 mL vials contains 2 mg levorphanol tartrate, 4.5 mg phenol preservative, sodium hydroxide to adjust pH to approximately 4.3 and Water for Injection.

Each tablet contains 2 mg levorphanol tartrate, lactose, corn starch, stearic acid and talc.

Brand Name: Levo Dromoran
Generic Name: Levorphanol

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