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Travatan

Drug Description
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Travatan
(travoprost ophthalmic solution) 0.004% Sterile

DRUG DESCRIPTION

Travoprost is a synthetic prostaglandin F analogue. Its chemical name is isopropyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2- [(1E,3R)-3-hydroxy-4-[(α,α,α- trifluoro-m-tolyl)oxy]-1-butenyl]cyclopentyl]-5-heptenoate. It has a molecular formula of C26H35F3O6 and a molecular weight of 500.56. The chemical structure of travoprost is:

Travatan (travoprost) structural formula illustration

Travoprost is a clear, colorless to slightly yellow oil that is very soluble in acetonitrile, methanol, octanol, and chloroform. It is practically insoluble in water.

TRAVATAN® Ophthalmic Solution 0.004% is supplied as sterile, buffered aqueous solution of travoprost with a pH of approximately 6.0 and an osmolality of approximately 290 mOsmol/kg.

Each mL of TRAVATAN® 0.004% contains 40 µg travoprost. Benzalkonium chloride 0.015% is added as a preservative. Inactive ingredients are: polyoxyl 40 hydrogenated castor oil, tromethamine, boric acid, mannitol, edetate disodium, sodium hydroxide and/or hydrochloric acid (to adjust pH) and purified water.

Brand Name: Travatan
Generic Name: Travoprost

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