Each mL of CELESTONE SOLUSPAN* Injectable Suspension contains: 3.0 mg betamethasone as betamethasone sodium phosphate; 3.0 mg betamethasone acetate; 7.1 mg dibasic sodium phosphate; 3.4 mg monobasic sodium phosphate; 0.1 mg edetate disodium; and 0.2 mg benzalkonium chloride. It is a sterile, aqueous suspension with a pH between 6.8 and 7.2.

The formula for betamethasone sodium phosphate is C₂₂H₂₈FNa₂O₈P with a molecular weight of 516.41. Chemically it is 9-Fluoro-11b, 17,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione 21-(disodium phosphate).

The formula for betamethasone acetate is C₂₄H₃₁FO₆with a molecular weight of 434.50. Chemically it is 9-Fluoro-11b, 17,21-trihydroxy-16b-methylpregna-1, 4-diene-3,20-dione 21-acetate.

Betamethasone sodium phosphate is a white to practically white, odorless powder, and is hygroscopic. It is freely soluble in water and in methanol, but is practically insoluble in acetone and in chloroform.

Betamethasone acetate is a white to creamy white, odorless powder that sinters and resolidifies at about 165°C, and remelts at about 200°C-220°C with decomposition. It is practically insoluble in water, but freely soluble in acetone, and is soluble in alcohol and in chloroform.

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