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Prolixin

Drug Description
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DRUG DESCRIPTION

FLUPHENAZINE HCl TABLETS, USP
1 mg, 2.5 mg, 5 mg and 10 mg

Fluphenazine hydrochloride is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia. Chemically it is 4-[3-[2-(Trifluor-omethyl) phenothiazin-10-yl] propyl]-1-piperazineethanol dihydrochloride. Its molecular formular is C22H26F3N3OS·2HCl and its molecular weight is 510.44, with structure:

Each tablet, for oral administration, contains 1 mg, 2.5 mg, 5 mg, or 10 mg of fluphenazine hydrochloride per tablet.

Inactive ingredients are: hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinzed starch, sodium lauryl sulfate and titanium dioxide. The following additional product specific inactive ingredients are employed:

    1 mg- Hydroxypropyl cellulose, talc
    2.5 mg- Glyceryl triacetate, lecithin, polydextrose, sodium alginate
    5 mg- Hydroxypropyl cellulose
    10 mg- Glyceryl triacelate, polydextrose, polyvinyl-pyrrolidone, sodium alginate

The following coloring agents are employed:

    1 mg- Calcium sulfate, titanium dioxide
    2.5 mg- D&C Yellow #10 Aluminum Lake. FD&C Yellow #6 Aluminum Lake
    5 mg- D&C Yellow #10 Aluminum Lake. FD&C Yellow #6 Aluminum Lake, FD&C Blue #1 Aluminum Lake
    10 mg- FD&C Yellow #6 Aluminum Lake
Brand Name: Prolixin
Generic Name: Fluphenazine

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