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Isuprel

Drug Description
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ISUPREL®
Isoproterenol Hydrochloride Injection, USP
Sterile Injection 1:5000

DRUG DESCRIPTION

Isoproterenol hydrochloride is 3,4-Dihydroxy-a-[(isopropylamino) methyl] benzyl alcohol hydrochloride, a synthetic sympathomimetic amine that is structurally related to epinephrine but acts almost exclusively on beta receptors. The molecular formula is C11H17NO3 · HCl. It has a molecular weight of 247.72 and the following structural formula:

Isoproterenol hydrochloride is a racemic compound.

Each milliliter of the sterile 1:5000 solution contains:

ISUPREL, brand of isoproterenol hydrochloride injection, USP 0.2 mg
Lactic Acid 0.12mg
Sodium Chloride 7.0 mg
Sodium Lactate 1.8mg
Sodium Metabisulfite (as preservative) 1.0 mg
Water for Injection qs ad 1.0 mL

The pH is adjusted between 2.5 and 4.5 with hydrochloric acid. The air in the ampuls has been displaced by nitrogen gas.

The sterile 1:5000 solution is nonpyrogenic and can be administered by the intravenous, intramuscular, subcutaneous, or intracardiac routes.

Brand Name: Isuprel
Generic Name: Isoproterenol

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