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Vermox
CLINICAL PHARMACOLOGY
Vermox
Following administration of 100 mg twice daily for three consecutive days, plasma levels of VERMOX® (mebendazole) and its primary metabolite, the 2-amine, do not exceed 0.03 µg/mL and 0.09 µg/mL, respectively. All metabolites are devoid of anthelmintic activity. In man, approximately 2% of administered VERMOX® is excreted in urine and the remainder in the feces as unchanged drug or a primary metabolite.
Mode of Action
VERMOX® inhibits the formation of the worms' microtubules and causes the worms' glucose depletion.
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