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DRUG DESCRIPTION

Pentamidine Isethionate For Injection

Pentamidine Isethionate For Injection, an antiprotozoal agent, is a nonpyrogenic, lyophilized product. After reconstitution, it should be administered by intramuscular or intravenous (I.M. or I.V.) routes (see DOSAGE AND ADMINISTRATION).

Pentamidine isethionate is a white, crystalline powder soluble in water and glycerin and insoluble in ether, acetone, and chloroform. It is chemically designated as 4,4'- diamidino-diphenoxypentane di (b-hydroxyethanesulfonate). The molecular forumula is C23H36N4O10S2 and the molecular weight is 592.68.

Each vial contains:

Pentamidine isethionate ...................................... 300 mg

May contain sodium hydroxide and/or hydrochloric acid for pH adjustment.

Pentamidine Isethionate For Injection is prepared as a solution and lyophilized in its final container.

Brand Name: Nebupent
Generic Name: Pentamidine Isethionate

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