CloseClose
Find a Drug
Advanced Search

Professional

Synvisc

Drug Description
font size

SYNVISC®
HYLAN G-F 20

Caution: Federal law restricts this device to sale by or on the order of a physician (or properly licensed practitioner).

DRUG DESCRIPTION

Synvisc® (hylan G-F 20) is an elastoviscous fluid containing hylan polymers produced from chicken combs. Hylans are derivatives of hyaluronan (sodium hyaluronate), a natural complex sugar of the gly-cosaminoglycan family. Hyaluronan is a long-chain polymer containing repeating disaccharide units of Na-glucuronate-N-acetylglucosamine.

DETAILED DEVICE DESCRIPTION

Synvisc contains hylan A (average molecular weight 6, 000, 000) and hylan B hydrated gel in a buffered physiological sodium chloride solution, pH 7. 2. Synvisc has an elasticity (storage modulus G') at 2. 5 H of 111 ± 13 Pascals (Pa) and a viscosity (loss modulus G") of 25 ± 2 Pa (elasticity and viscosity of knee synovial fluid of 18 to 27-year-old humans measured with a comparable method at 2. 5 Hz:G' = 117 ± 13 Pa; G" = 45 ± 8 Pa. )

Each syringe of Synvisc contains:

  

Hylan polymers (hylan A + hylan B)

16 mg

Sodium chloride

17 mg

Disodium hydrogen phosphate

0. 32 mg

Sodium dihydrogen phosphate monohydrate

0. 08 mg

Water for injection

q. s. to 2. 0 mL
Brand Name: Synvisc
Generic Name: Hylan G-F 20
Bookmark this page:



Privacy Policy

Arthritis

Get the latest treatment options

WebMD Symptom Checker - Start Here Ringworm Slideshow: Watch and Learn

Guided Knee Replacement Guided Knee Replacement
Computers are making it easier for surgeons to achieve a near-perfect fit when it comes to knee replacement surgery. See more WebMD Videos »