font size

Charcot-Marie-Tooth-Disease (cont.)

What research is being done on Charcot-Marie-Tooth disease?

The NINDS supports research on CMT and other peripheral neuropathies in an effort to learn how to better treat, prevent, and even cure these disorders. Ongoing research includes efforts to identify more of the mutant genes and proteins that cause the various disease subtypes, efforts to discover the mechanisms of nerve degeneration and muscle atrophy with the hope of developing interventions to stop or slow down these debilitating processes, and efforts to find therapies to reverse nerve degeneration and muscle atrophy.

One promising area of research involves gene therapy experiments. Research with cell cultures and animal models has shown that it is possible to deliver genes to Schwann cells and muscle. Another area of research involves the use of trophic factors or nerve growth factors, such as the hormone androgen, to prevent nerve degeneration. Vitamin C has been studied in CMT1A and the results of a multicentric trial are due soon. Curcumin, a component of curry, is currently being studied as a treatment strategy in an animal model of CMT1B.

Medically reviewed by Edward Spence, MD; American Board of Pediatrics and American Board of Medical Genetics with subspecialties in Clinical Genetics, Clinical Biochemical Genetics, Clinical Molecular Genetics

Last updated: 5/12/2010 SOURCE:

"Charcot-Marie-Tooth Disease Fact Sheet." National Institute of Neurological Disorders and Stroke. 8 July 2013.


Medically Reviewed by a Doctor on 4/2/2014

Patient Comments

Viewers share their comments

Charcot-Marie-Tooth Disease - Symptoms and Signs Question: What symptoms and signs did you experience with Charcot-Marie-Tooth disease?
Charcot-Marie-Tooth Disease - Type Question: What type of Charcot-Marie-Tooth disease do you have, and how has it affected you?
Charcot-Marie-Tooth Disease - Treatment Question: What types of treatment have you received for Charcot-Marie-Tooth disease?
Source: MedicineNet.com
http://www.medicinenet.com/charcot-marie-tooth-disease/article.htm

Women's Health

Find out what women really need.

advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations

NIH talks about Ebola on WebMD