"The US Food and Drug Administration (FDA) today approved asfotase alfa (Strensiq, Alexion Pharmaceuticals) as the first-ever therapy for patients who develop hypophosphatasia, a rare metabolic bone disorder, in childhood.
(succimer) Capsules 100 mg
CHEMET (succimer) is an orally active, heavy metal chelating agent. The chemical name for succimer is meso 2, 3-dimercaptosuccinic acid (DMSA). Its empirical formula is C4H6O4S2 and molecular weight is 182.2. The meso-structural formula is:
Succimer is a white crystalline powder with an unpleasant, characteristic mercaptan odor and taste.
Each CHEMET opaque white capsule for oral administration, contains beads coated with 100 mg of succimer and is imprinted black with CHEMET 100. Inactive ingredients in medicated beads are: povidone, sodium starch glycolate, starch and sucrose. Inactive ingredients in capsule are: gelatin, iron oxide, titanium dioxide and other ingredients.
What are the possible side effects of succimer (Chemet)?
Seek emergency medical attention or contact your doctor immediately if you experience any of the following rare but serious side effects to succimer:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- skin rash or sores in the mouth; or
- signs of infection such as fever, sore throat, or coughing.
Other, less serious side effects may be more likely to occur. Continue to take succimer and talk to your doctor if you experience
- nausea, vomiting, or decreased...
What are the precautions when taking succimer (Chemet)?
Before taking succimer, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this medication passes into breast milk. However, since this medication is used for lead poisoning and lead may pass into breast milk, do not breast-feed while using this...
Last reviewed on RxList: 9/18/2013
This monograph has been modified to include the generic and brand name in many instances.
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