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Doses of 2300 mg/kg in the rat and 2400 mg/kg in the mouse produced ataxia, convulsions, labored respiration and frequently death. No case of overdosage has been reported in humans. Limited data indicate that succimer is dialyzable. In case of acute overdosage, induction of vomiting or gastric lavage followed by administration of an activated charcoal slurry and appropriate supportive therapy are recommended.
CHEMET (succimer) should not be administered to patients with a history of allergy to the drug.
Last reviewed on RxList: 8/1/2007
This monograph has been modified to include the generic and brand name in many instances.
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