Kawasaki disease is a very serious disease that can mimic many infections. When unrecognized and untreated, it can result in severe damage to the coronary arteries of the heart, resulting in heart attack and sudden death in children. Luckily, most pediatricians are taught to look out for Kawasaki disease and learn to recognize the illness based on common signs and symptoms. These include high prolonged fever (greater than five days), a rash, cracked and dry lips, red eyes, enlarged neck lymph nodes, and swelling of the hands and feet. Hospitalization is recommended, and administration of IVIG (immunoglobulin) and aspirin are necessary. This treatment, when started early enough in the course of illness, prevents progression of the heart problems. The cause remains unknown.