Chloroptic (Chloramphenicol) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

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Chloroptic

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Chloroptic®
(chloramphenicol) Ophthalmic Solution, USP 0.5% sterile

WARNING

Bone marrow hypoplasia including aplastic anemia and death has been reported following topical application of chloramphenicol. Chloramphenicol should not be used when less potentially dangerous agents would be expected to provide effective treatment.

DRUG DESCRIPTION

Chloroptic® (chloramphenicol ophthalmic solution, USP) is a topical anti-infective product for ophthalmic use.

Structural Formula

C₁₁H₁₂Cl₁₂N₂0₅

Mol Wt 323.13

Chemical Name:

D-threo-(-)-2,2-Dichloro-N-143-hydroxy-a-(hydroxymethyl)..

p-nitrophenethyl] acetamide

Contains:

Active: chloramphenicol	0.5% (5mg/ml)
Preservative: chlorobutanol (chloral deny.)	0.5%;

Inactives: polyethylene glycol 300; polyoxyl 40 stearate; sodium hydroxide or hydrochloric acid to adjust PH; and purified water.

What are the possible side effects of chloramphenicol ophthalmic (Chloroptic, Chloroptic S.O.P.)?

Serious side effects are not expected with this medication. Rarely, prolonged use of this medication has damaged bone marrow. Call your doctor if you experience extreme fatigue or unusual bleeding or bruising.

More commonly, some burning, stinging, irritation, itching, redness, blurred vision, or sensitivity to light may occur. Continue to use chloramphenicol ophthalmic and talk to your doctor about any side effects that you...

Read All Potential Side Effects and See Pictures of Chloroptic »

What are the precautions when taking chloramphenicol (Chloroptic)?

Before using chloramphenicol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: an eye infection due to a virus (e.g., herpes, varicella), another type of eye infection (e.g., tuberculosis, fungus), history of a bad reaction to chloramphenicol.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, anemia (low red blood cells), radiation therapy.

After you apply...

Read All Potential Precautions of Chloroptic »

Last reviewed on RxList: 1/2/2005
This monograph has been modified to include the generic and brand name in many instances.