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Chloramphenicol is a broad-spectrum antibiotic originally isolated from Streptomyces venezuelae. It is primarily bacteriostatic and acts by inhibition of protein synthesis by interfering with the transfer of activated amino acids from soluble RNA to ribosomes.
Chloramphenicol has been shown to be active against the following organisms:
streptococci, including Streptococcus pneumoniae
Aerobic gram-negative microorganisms:
Moraxella lucunata (Morax-Axenfeld bacillus)
This product does not provide adequate coverage against Pseudomonas aeruginosa or Serratia marcescens.
Bacteriological studies should be performed to determine the causative organisms and their susceptibilities to chloramphenicol.
Last reviewed on RxList: 1/2/2005
This monograph has been modified to include the generic and brand name in many instances.
Additional Chloroptic Information
- Chloroptic Drug Interactions Center: chloramphenicol opht
- Chloroptic Side Effects Center
- Chloroptic Overview including Precautions
- Chloroptic FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
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