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(Generic versions may still be available.)
Chioramphenicol should be used only in those serious infections for which less potentially dangerous drugs are ineffective or contraindicated. (See Boxed Warning)
Chloroptic (chloramphenicol) is indicated for the treatment of surface ocular infections involving the conjunctiva and/or cornea caused by chloramphenicol-susceptible organisms. Chloramphenicol is active against the following common bacterial eye pathogens: Staphylococcus aureus; streptococci, including Streptococcus pneumoniae, Escherichia coli, Haemophilus influenzea, Klebsiella/Enterobacter species; Moraxella lacunata (Morax-Axenfeld bacillus); and Neisseria species. Chloramphenicol does not provide adequate coverage against: Pseudomonas aeruginosa or Serratia marcescens.
DOSAGE AND ADMINISTRATION
One or two drops 4 to 6 times a day for the first 72 hours should be placed in the lower conjunctival sac. Treatment should be continued for approximately 7 days but should not be continued for more than three weeks without re-evaluation by the prescribing physician.
Chloroptic (chloramphenicol ophthalmic solution, USP) is supplied in the following sizes:
2.5 mL - NDC 11980-109-03
7.5 mL - NDC 11980-109-08
NOTE : Refrigerate until dispensed. Then store below 30°C (86F). Discard solution within 21 days from date dispensed.
U.S. Patent 3,702,364 Revised July 2000 ©2000 Allergan, Inc. Irvine, CA 92612This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 1/2/2005
Additional Chloroptic Information
- Chloroptic Drug Interactions Center: chloramphenicol opht
- Chloroptic Side Effects Center
- Chloroptic Overview including Precautions
- Chloroptic FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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