"People with untreated obstructive sleep apnea (OSA) and exudative age-related macular degeneration (AMD) may have decreased response to bevacizumab therapy, according to a study published in the April issue of Retina.
DOSAGE AND ADMINISTRATION
Shake vial vigorously before withdrawing each dose.
Parenteral drug products should be inspected visually for presence of particulate matter and discoloration prior to use.
The primary immunizing course consists of two doses administered one week to one month or more apart. The table below summarizes the recommended doses for both primary and booster immunizations by age, volume (mL), and route of administration. 3,5 The intracutaneous (intradermal) route is satisfactory for persons 5 years of age and older, but higher levels of antibody may be achieved in children less than 5 years old by the subcutaneous or intramuscular routes.
|Route & Age|
|Dose number||Intradermal||Subcutaneous or Intramuscular|
|5 years |
|6 mos- |
|1 & 2||0.2 mL||0.2 mL||0.3 mL||0.5 mL|
|Boosters||0.2 mL||0.2 mL||0.3 mL||0.5 mL|
In areas where cholera is epidemic or endemic, booster doses should be given every six months.
The primary immunizing series need never be repeated for booster doses to be effective.
Cholera Vaccine, USP, is supplied as 1.5 and 20 mL vials.
Keep between 2° and 8°C (35° and 46°F).
Keep from freezing.
- Recommendation of the Immunization Practices Advisory Committee (ACIP). General recommendations on immunization. MMWR 32(1):1, 1983.
- Recommendations of the Immunization Practices Advisory Committee (ACIP). Yellow fever vaccine. MMWR 32(52):679, 1984.
- Recommendation of the Public Health Service Advisory Committee on Immunization Practices--Cholera Vaccine. MMWR 27(20):173, 1978.
- GANGAROSA, E. and FAICH, G.: Cholera: The risk to American travelers. Ann. Int. Med. 74:412, 1971.
- Report of the Committee on Infectious Diseases, American Academy of Pediatrics, 1982 (Red Book).
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Last reviewed on RxList: 12/8/2004
Additional Cholera Vaccine Information
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