In this Article
- What other names is Choline known by?
- What is Choline?
- How does Choline work?
- Are there safety concerns?
- Are there any interactions with medications?
- Dosing considerations for Choline.
Taking high doses of choline by mouth is POSSIBLY UNSAFE for adults. Doses over the Daily Upper Intake Levels (see dosage section below) are more likely to cause side effects such as sweating, a fishy body odor, gastrointestinal distress, diarrhea, and vomiting.
There is some concern that increasing dietary choline intake might increase the risk of cancer of the colon and rectum. One study found that women eating a diet that contains a lot of choline have an increased the risk of colon cancer. However, more research is still needed to determine the effects of diet on colon cancer.
Special Precautions & Warnings:Children: Choline is LIKELY SAFE for most children when taken by mouth in appropriate amounts. Taking high doses of choline by mouth is POSSIBLY UNSAFE for children due to the increased risk of side effects.
Pregnancy and breast-feeding: Choline is LIKELY SAFE when taken by mouth and used appropriately. Doses up to 3 grams daily for pregnant and breast-feeding women up to 18 years of age, and 3.5 grams daily for women 19 years and older are not likely to cause unwanted side effects. There isn't enough information available about the safety of choline used in higher doses in pregnant or lactating women. It's best to stick to recommended doses.
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