Ciloxan Ophthalmic Solution
"In a traditional corneal transplant, the central part of the cornea is removed and a donor cornea is sutured in its place. Image courtesy of Dr. Edward Holland, University of Cincinnati.
Ten years after a transplant, a cornea fro"...
Ciloxan Ophthalmic Solution
(ciprofloxacin HCL ophthalmic solution) 0.3% as Base
CILOXAN® (ciprofloxacin HCL ophthalmic solution) is a synthetic, sterile, multiple dose, antimicrobial for topical use. Ciprofloxacin is a fluoroquinolone antibacterial active against a broad spectrum of gram positive and gram-negative ocular pathogens. It is available as the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline-carboxylic acid. It is a faint to light yellow crystalline powder with a molecular weight of 385.8. Its empirical formula is C17H18FN3O3Â·HClÂ·H2O and its chemical structure is as follows:
Ciprofloxacin differs from other quinolones in that it has a fluorine atom at the 6-position, a piperazine moiety at the 7-position, and a cyclopropyl ring at the 1-position.
Each mL of CILOXAN Ophthalmic Solution (ciprofloxacin hcl ophthalmic solution) contains: Active: ciprofloxacin HCl 3.5 mg equivalent to 3 mg base. Preservative: benzalkonium chloride 0.006%. Inactives: sodium acetate, acetic acid, mannitol 4.6%, edetate disodium 0.05%, hydrochloric acid and/or sodium hydroxide (to adjust pH) and Purified Water. The pH is approximately 4.5 and the osmolality is approximately 300 mOsm.
What are the possible side effects of ciprofloxacin ophthalmic (Ciloxan)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; slow heart rate, weak pulse, fainting; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- severe swelling, itching, burning, redness, or discomfort in or around your eye;
- eye pain, vision changes, increased sensitivity of your eyes to light;
- signs of new infection, such as drainage, crusting, or oozing of your eyes or eyelids;
- the first sign of any skin...
What are the precautions when taking ciprofloxacin hcl ophthalmic solution (Ciloxan Ophthalmic Solution)?
Before using ciprofloxacin, tell your doctor or pharmacist if you are allergic to it; or to other quinolones (e.g., levofloxacin, moxifloxacin); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: contact lens use, other eye problems.
Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.
This medication should be...
Last reviewed on RxList: 3/28/2006
This monograph has been modified to include the generic and brand name in many instances.
Additional Ciloxan Ophthalmic Solution Information
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