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Ciloxan Ophthalmic Solution

"In laboratory tests, researchers have used electrical stimulation of retinal cells to produce the same patterns of activity that occur when the retina sees a moving object. Although more work remains, this is a step toward restoring natural, high"...

Ciloxan Ophthalmic Solution

INDICATIONS

CILOXAN Ophthalmic Solution is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the conditions listed below:

Corneal Ulcers

Pseudomonas aeruginosa

Serratia marcescens *

Staphylococcus aureus

Staphylococcus epidermidis

Streptococcus pneumoniae

Streptococcus (Viridans Group) *

Conjunctivitis

Haemophilus influenzae

Staphylococcus aureus

Staphylococcus epidermidis

Streptococcus pneumoniae

*Efficacy for this organism was studied in fewer than 10 infections.

DOSAGE AND ADMINISTRATION

Corneal Ulcers: The recommended dosage regimen for the treatment of corneal ulcers is two drops into the affected eye every 15 minutes for the first six hours and then two drops into the affected eye every 30 minutes for the remainder of the first day. On the second day, instill two drops in the affected eye hourly. On the third through the fourteenth day, place two drops in the affected eye every four hours. Treatment may be continued after 14 days if corneal re-epithelialization has not occurred.

Bacterial Conjunctivitis: The recommended dosage regimen for the treatment of bacterial conjunctivitis is one or two drops instilled into the conjunctival sac(s) every two hours while awake for two days and one or two drops every four hours while awake for the next five days.

HOW SUPPLIED

As a sterile ophthalmic solution in Alcons DROP-TAINER? dispensing system consisting of a natural low density polyethylene bottle and dispensing plug and tan polypropylene closure. Tamper evidence is provided with a shrink band around the closure and neck area of the package.

2.5 mL in 8 mL bottle - NDC 0065-0656-25

5 mL in 8 mL bottle - NDC 0065-0656-05

10 mL in 10 mL bottle - NDC 0065-0656-10

STORAGE: Store at 2°- 25°C (36°- 77°F). Protect from light.

ANIMAL PHARMACOLOGY

Ciprofloxacin and related drugs have been shown to cause arthropathy in immature animals of most species tested following oral administration. However, a one-month topical ocular study using immature Beagle dogs did not demonstrate any articular lesions.

Rx only

U.S. Patent No. 4,670,444
Alcon? Pharmaceuticals
ALCON LABORATORIES, INC. Fort Worth, Texas 76134 USA
Revised: September 2004?2003 Alcon, Inc
FDA revision date:2/07/06

Last reviewed on RxList: 3/28/2006
This monograph has been modified to include the generic and brand name in many instances.

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