Crohn's Disease Resources
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Crohn's disease (also spelled Crohn disease) is a chronic inflammatory disease of the intestines. It primarily causes ulcerations (breaks in the lining) of the small and large intestines, but can affect the digestive system anywhere from the mouth to the anus. It is named after the physician who described the disease in 1932. It also is called granulomatous enteritis or colitis, regional enteritis, ileitis, or terminal ileitis.
Crohn's disease is related closely to another chronic inflammatory condition that involves only the colon called ulcerative colitis. Together, Crohn's disease and ulcerative colitis are frequently referred to as inflammatory bowel disease (IBD). Ulcerative colitis and Crohn's disease have no medical cure. Once the diseases begin, they tend to fluctuate between periods of inactivity (remission) and activity (relapse).
Inflammatory bowel disease affects approximately 500,000 to two million peop...
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Medical Editor: Charles Patrick Davis, MD, PhD
Cimzia, a TFN blocker, is indicated for reducing signs and symptoms of Crohn's disease and maintaining clinical response in adult patients with moderately to severely active disease. Side effects include but are not limited to: serious infections, malignancies, and heart failure.
Cimzia is administered by subcutaneous injection available in 200mg strength per ml in sterile vials. Patients treated with Cimzia are at an increased risk for developing serious infections involving various organ systems and sites that may lead to hospitalization or death. An increased risk of serious infections has been seen in clinical studies of other TNF blocking agents used in combination with anakinra or abatacept with no added benefit. Do not give live vaccines including attenuated vaccines with Cimzia. Cimzia should only be used during pregnancy only if clearly needed. A decision should be made whether to discontinue nursing of discontinue the drug, taking into account the importance of the drug to the mother.
Our Cimzia (certolizumab pegol) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
CIMZIA is indicated for reducing signs and symptoms of Crohn's disease and maintaining clinical response in adult patients with moderately to severely active disease who have had an inadequate response to conventional therapy.
CIMZIA is indicated for the treatment of adults with moderately to severely active rheumatoid arthritis (RA).
Read the complete drug monograph for Cimzia »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Serious and sometimes fatal infections may occur during treatment with certolizumab. Stop using certolizumab and call your doctor right away if you have signs of infection such as:
Call your doctor at once if you have any of these other serious ...
Read the complete patient information for Cimzia »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
HOW TO USE: Read the Medication Guide provided by your pharmacist before you start using certolizumab and each time you get a refill. If you have any questions, consult you...
Read the complete consumer information for Cimzia »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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