Recommended Topic Related To:

Cinryze

"Feb. 25, 2013 (San Antonio, Texas) -- The asthma drug Xolair appears to be a safe and effective treatment for chronic hives, a new study shows.

The results of the study were presented at a news conference here at the American Academy"...

Cinryze

Cinryze

OVERDOSE

The maximum dose administered in clinical studies was 4000 Units given over approximately 5 hours (an average dose of 57 Units/kg) and 9000 Units given over a 7 day period. There have been no overdosages of CINRYZE (c1 esterase inhibitor [human] freeze dried powder) reported during clinical studies.

In vitro and in vivo animal thrombogenicity studies with CINRYZE (c1 esterase inhibitor [human] freeze dried powder) showed a potential for clot formation when CINRYZE (c1 esterase inhibitor [human] freeze dried powder) was administered at doses 14 times the recommended clinical dose (greater than 200U/kg). Thrombotic events have been reported in association with C1 esterase inhibitor products when used off-label at high doses.6 Animal studies have supported a concern about the risk of thrombosis from intravenous administration of C1 esterase inhibitor products.7 (see Animal Toxicology and/or Pharmacology and Thrombotic events in WARNINGS AND PRECAUTIONS).

CONTRAINDICATIONS

CINRYZE (c1 esterase inhibitor [human] freeze dried powder) is contraindicated in patients who have manifested life-threatening immediate hypersensitivity reactions, including anaphylaxis to the product.

REFERENCES

6. Arzneimittelkommission der Deutschen Aertzteschaft. Schwerwiegende Thrombenbildung nach Berinert HS. Dtsch Aerztebl. 2000; 97:B-864

7. Horstick, G et al, 2002. Circulation 104:3125-3131

Last reviewed on RxList: 10/2/2009
This monograph has been modified to include the generic and brand name in many instances.

A A A

Cinryze - User Reviews

Cinryze User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Cinryze sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Allergies & Asthma

Improve treatments & prevent attacks.

Health Resources
advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations