Brand Names: Cipro, Cipro XR, Proquin XR

Generic Name: ciprofloxacin (oral) (Pronunciation: SIP roe FLOX a sin)

• What is ciprofloxacin (Cipro XR)?
• What are the possible side effects of ciprofloxacin (Cipro XR)?
• What is the most important information I should know about ciprofloxacin (Cipro XR)?
• What should I discuss with my healthcare provider before taking ciprofloxacin (Cipro XR)?
• How should I take ciprofloxacin (Cipro XR)?
• What happens if I miss a dose (Cipro XR)?
• What happens if I overdose (Cipro XR)?
• What should I avoid while taking ciprofloxacin (Cipro XR)?
• What other drugs will affect ciprofloxacin (Cipro XR)?
• Where can I get more information?

What is ciprofloxacin (Cipro XR)?

Ciprofloxacin is an antibiotic in a group of drugs called fluoroquinolones (flor-o-KWIN-o-lones). Ciprofloxacin fights bacteria in the body.

Ciprofloxacin is used to treat different types of bacterial infections.

Ciprofloxacin may also be used for other purposes not listed in this medication guide.

Cipro 100 mg

round, white, imprinted with CIPRO, 100

Cipro 250 mg

round, white, imprinted with CIPRO, 250

Cipro 500 mg

oblong, white, imprinted with CIPRO, 500

Cipro 750 mg

oblong, white, imprinted with CIPRO, 750

Cipro XR 1000 mg

oblong, white, imprinted with BAYER, C1000 QD

Cipro XR 500 mg

oblong, white, imprinted with BAYER, C500 QD

Ciprofloxacin 250 mg-APO

round, white, imprinted with APO, CIP 250

Ciprofloxacin 250 mg-BAR

round, white, imprinted with b 814, 250

Ciprofloxacin 250 mg-DRR

oval, white, imprinted with R, 126

Ciprofloxacin 250 mg-IVA

oval, white, imprinted with LOGO 5311, 250

Ciprofloxacin 250 mg-PAR

round, white, imprinted with G, CF 250

Ciprofloxacin 500 mg-APO

white, imprinted with APO, CIP500

Ciprofloxacin 500 mg-BAR

oblong, white, imprinted with b815, 500

Ciprofloxacin 500 mg-DRR

oval, white, imprinted with R, 127

Ciprofloxacin 500 mg-IVA

oval, white, imprinted with 500, LOGO 5312

Ciprofloxacin 500 mg-PAR

oblong, white, imprinted with G, CF500

Ciprofloxacin 500 mg-RAN

oblong, white, imprinted with RX710

Ciprofloxacin 500 mg-TEV

oblong, white, imprinted with 93, 0864

Ciprofloxacin 750 mg-APO

white, imprinted with APO, CIP750

Ciprofloxacin 750 mg-BAR

oblong, white, imprinted with b816, 750

Ciprofloxacin 750 mg-DRR

oblong, white, imprinted with R, 128

Ciprofloxacin 750 mg-IVA

oval, white, imprinted with Logo 5313, 750

Ciprofloxacin 750 mg-TEV

oblong, white, imprinted with 93, 0865

What are the possible side effects of ciprofloxacin (Cipro XR)?

Stop using ciprofloxacin and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using ciprofloxacin and call your doctor at once if you have any of these serious side effects:

• dizziness, fainting, fast or pounding heartbeat;
• sudden pain or swelling near your joints (especially in your arm or ankle);
• diarrhea that is watery or bloody;
• confusion, hallucinations, depression, unusual thoughts or behavior;
• seizure (convulsions);
• pale or yellowed skin, dark colored urine, fever, weakness;
• urinating less than usual or not at all;
• easy bruising or bleeding;
• numbness, tingling, or unusual pain anywhere in your body;
• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
• the first sign of any skin rash, no matter how mild.

Less serious side effects may include:

• nausea, vomiting;
• dizziness or drowsiness;
• blurred vision;
• feeling nervous, anxious, or agitated;
• sleep problems (insomnia or nightmares); or
• increased sensitivity of the skin to sunlight.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about ciprofloxacin (Cipro XR)?

You should not use this medication if you are taking tizanidine (Zanaflex), or if you are allergic to ciprofloxacin or similar antibiotics such as levofloxacin (Levaquin), moxifloxacin (Avelox), ofloxacin (Floxin), norfloxacin (Noroxin), lomefloxacin (Maxaquin), and others.

Do not take ciprofloxacin with dairy products such as milk or yogurt, or with calcium-fortified juice. You may eat or drink dairy products or calcium-fortified juice with a regular meal, but do not use them alone when taking ciprofloxacin. They could make the medication less effective.

Before taking ciprofloxacin, tell your doctor if you have kidney or liver disease, myasthenia gravis, joint problems, diabetes, a history of seizures, low levels of potassium in your blood (hypokalemia), or a personal or family history of "Long QT syndrome."

Avoid taking antacids, vitamin or mineral supplements, sucralfate (Carafate), or didanosine (Videx) powder or chewable tablets within 6 hours before or 2 hours after you take ciprofloxacin. These other medicines can make ciprofloxacin much less effective when taken at the same time.

Ciprofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. These effects may be more likely to occur if you are over 60, if you take an oral steroid medication, or if you have had a kidney, heart, or lung transplant. Stop taking ciprofloxacin and call your doctor at once if you have sudden pain, swelling, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions.