Recommended Topic Related To:

Ciprodex

"Feb. 13, 2013 -- A new illness similar to the deadly SARS virus has probably spread from person to person in the U.K.

Previous cases of this new virus, a coronavirus, have been seen in people who've returned from visits abroad. The la"...

Ciprodex

CIPRODEX®
(ciprofloxacin 0.3% and dexamethasone 0.1%)
Sterile Otic Suspension

DRUG DESCRIPTION

CIPRODEX® (ciprofloxacin 0.3% and dexamethasone 0.1%) Sterile Otic Suspension contains the synthetic broad-spectrum antibacterial agent, ciprofloxacin hydrochloride, combined with the anti-inflammatory corticosteroid, dexamethasone, in a sterile, preserved suspension for otic use. Each mL of CIPRODEX® (ciprofloxacin and dexamethasone ) Otic contains ciprofloxacin hydrochloride (equivalent to 3 mg ciprofloxacin base), 1 mg dexamethasone, and 0.1 mg benzalkonium chloride as a preservative. The inactive ingredients are boric acid, sodium chloride, hydroxyethyl cellulose, tyloxapol, acetic acid, sodium acetate, edetate disodium, and purified water. Sodium hydroxide or hydrochloric acid may be added for adjustment of pH.

Ciprofloxacin, a fluoroquinolone is available as the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid. The empirical formula is C17H18FN3O3•HCl•H2O and the structural formula is:

CIPRODEX® (ciprofloxacin 0.3% and dexamethasone 0.1%) Structural Formula Illustration

Dexamethasone, 9-fluoro-11(beta),17,21-trihydroxy-16(alpha)-methylpregna-1,4-diene-3,20-dione, is an anti-inflammatory corticosteroid. The empirical formula is C22H29FO5 and the structural formula is:

CIPRODEX® (ciprofloxacin 0.3% and dexamethasone 0.1%) Structural Formula Illustration

What are the possible side effects of ciprofloxacin and dexamethasone otic (Ciprodex)?

Stop using ciprofloxacin and dexamethasone otic and seek emergency medical attention or notify your doctor if you experience:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • skin rash; or
  • ear drainage, discharge, or worsening pain.

Other less serious side effects may also occur such as ear discomfort or itching or an unusual taste in the mouth. Continue to use the medication and talk to your doctor if these side effects seem excessive or unusual.

Side...

Read All Potential Side Effects and See Pictures of Ciprodex »

What are the precautions when taking ciprofloxacin and dexamethasone (Ciprodex)?

Before using this medication, tell your doctor or pharmacist if you are allergic to quinolone antibiotics (e.g., ciprofloxacin, levofloxacin), or to corticosteroids (e.g., dexamethasone, prednisone); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: an ear infection caused by a virus (e.g., herpes simplex).

Before using this medication, tell your doctor or pharmacist your medical history.

This medication should be used only when clearly...

Read All Potential Precautions of Ciprodex »

Last reviewed on RxList: 8/17/2007
This monograph has been modified to include the generic and brand name in many instances.

A A A

Ciprodex - User Reviews

Ciprodex User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Ciprodex sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Women's Health

Find out what women really need.