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Ciprodex Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Ciprodex (ciprofloxacin and dexamethasone) is a combination of a fluoroquinolone antibiotic and a steroid used to treat ear infections. Common side effects of Ciprodex include discomfort, pain, or itching in the ear, or unusual taste in the mouth. Contact your doctor if you experience serious side effects of Ciprodex including allergic reaction, rash, ear drainage, ear discharge, or worsening pain.
The usual recommended dosage of Ciprodex in patients age 6 months and older is four drops instilled into the affected ear twice daily for seven days. Do not use other ear drops during treatment with Ciprodex without first talking to your doctor. Other drugs may interact with Ciprodex. Talk to your doctor before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products. Ciprodex should be used only when prescribed during pregnancy. This medication passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.
Our Ciprodex (ciprofloxacin and dexamethasone) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Ciprodex in Detail - Patient Information: Side Effects
Stop using ciprofloxacin and dexamethasone otic and seek emergency medical attention or notify your doctor if you experience:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- skin rash; or
- ear drainage, discharge, or worsening pain.
Other less serious side effects may also occur such as ear discomfort or itching or an unusual taste in the mouth. Continue to use the medication and talk to your doctor if these side effects seem excessive or unusual.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Ciprodex (Ciprofloxacin and Dexamethasone )
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Ciprodex Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Use of this medication for prolonged or repeated periods may result in a new fungal ear infection. Do not use this medication for longer than prescribed. Contact your doctor if you notice new or worsening symptoms.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Ciprodex (Ciprofloxacin and Dexamethasone )
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Ciprodex FDA Prescribing Information: Side Effects
In Phases II and III clinical trials, a total of 937 patients were treated with CIPRODEX® (ciprofloxacin and dexamethasone ) Otic. This included 400 patients with acute otitis media with tympanostomy tubes and 537 patients with acute otitis externa. The reported treatment-related adverse events are listed below:
Acute Otitis Media in pediatric patients with tympanostomy tubes
The following treatment-related adverse events occurred in 0.5% or more of the patients with non-intact tympanic membranes.
|Adverse Event||Incidence (N=400)|
|Ear precipitate (residue)||0.5%|
The following treatment-related adverse events were each reported in a single patient: tympanostomy tube blockage; ear pruritus; tinnitus; oral moniliasis; crying; dizziness; and erythema.
Acute Otitis Externa
The following treatment-related adverse events occurred in 0.4% or more of the patients with intact tympanic membranes.
|Adverse Event||Incidence (N=537)|
|Superimposed ear infection||0.6%|
The following treatment-related adverse events were each reported in a single patient: ear discomfort; decreased hearing; and ear disorder (tingling).
Read the entire FDA prescribing information for Ciprodex (Ciprofloxacin and Dexamethasone )
Additional Ciprodex Information
Ciprodex - User Reviews
Ciprodex User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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