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Clarinex-D 12hr

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Clarinex-D 12hr

Clarinex-D 12hr


Patients should be instructed to use CLARINEX-D® 12 HOUR (desloratadine and pseudoephedrine sulfate) Extended Release Tablets as directed. As there are no food effects on bioavailability, patients can be instructed that CLARINEX-D® 12 HOUR (desloratadine and pseudoephedrine sulfate) Extended Release Tablets may be taken without regard to meals. Patients should be advised not to increase the dose or dosing frequency as studies have not demonstrated increased effectiveness and at higher doses, somnolence may occur. Patients should also be advised against the concurrent use of CLARINEX-D® 12 HOUR (desloratadine and pseudoephedrine sulfate) Extended Release Tablets with over-the-counter antihistamines and decongestants.

Patients should be instructed not to break or chew the tablet; swallow whole.

Patients who are hypersensitive to this product or to any of its ingredients should not use this product. Due to its pseudoephedrine component, this product should not be used by patients with narrow-angle glaucoma, urinary retention, or by patients receiving a monoamine oxidase (MAO) inhibitor or within 14 days of stopping use of an MAO inhibitor. It also should not be used by patients with severe hypertension or severe coronary artery disease.

CLARINEX-D® 12 HOUR (desloratadine and pseudoephedrine sulfate) Extended Release Tablets should generally be avoided in patients with hepatic impairment and in patients with renal impairment.

Patients who are or may become pregnant should be told that this product should be used in pregnancy or during lactation only if the potential benefit justifies the potential risk to the fetus or nursing infant.

Last reviewed on RxList: 2/4/2009
This monograph has been modified to include the generic and brand name in many instances.


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